Possible benefits of short-chain fatty acids (SCFAs) for optimizing weight loss and metabolism.

What are SCFAs and why are they important to human health?

Short-chain fatty acids (SCFAs) are produced in the gut by friendly bacteria. The main ones produced in the gut that are important in human health are butyrate, propionate, and acetate. The body processes these short-chain fatty acids, but they also interact with several systems in the body in unique ways that have beneficial effects on metabolism.

Why should we take them though? Don’t gut bacteria produce enough SCFAs by themselves? Many people don’t have healthy gut flora. They also might not get enough fiber in their diet. Also, by taking supplemental SCFAs, it’s also possible to take them in more substantial amounts than would typically be produced in the gut without consuming enormous amounts of fiber. Taking larger than average amounts of short-chain fatty acids can be useful for biohacking purposes such as enhanced weight loss.

Some Research on SCFAs

  • Oral administration of SCFAs could reduce fat gain in pigs via reducing fat storage and enhancing fat burning. Study
  • Butyrate and propionate protect against diet-induced obesity and regulate gut hormones. Study
  • Acute oral sodium propionate supplementation raises resting energy expenditure and fat burning in fasted humans.Study
  • Propionate. Anti-obesity and satiety enhancing factor? Study.

How I am taking them

  • Sodium Butyrate and Propionate Supplement:

  • Apple Cider Vinegar Supplement ( for increasing acetate ) :

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